Name:  Nifedipine

Synonyms:  Dimethyl 1,4-dihydro-2,6-dimethyl-4-(2'-nitrophenyl)-3,5-pyridinedicarboxylate; 1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester

Molecular Structure:  

Molecular Formula:  C₁₇H₁₈N₂O₆

Molecular Weight:  346.34

CAS Number:  21829-25-4

EINECS:  244-598-3

 

Nifedipine is a dihydropyridine calcium channel blocker. Its main uses are as an antianginal (especially in Prinzmetal's angina) and antihypertensive, although a large number of other uses have recently been found for this agent, such as Raynaud's phenomenon, premature labor, and painful spasms of the esophagus in cancer and tetanus patients. Nifedipine is also commonly used for the small subset of pulmonary hypertension patients whose symptoms respond to calcium channel blockers.

The approved uses for nifedipine are the long-term treatment of hypertension (high blood pressure) and angina pectoris. In hypertension, recent clinical guidelines generally favour diuretics and ACE inhibitors, although calcium channel antagonists are still favoured as primary treatment for older black patients. Nifedipine has been used frequently as a tocolytic (agent that delays premature labor). A Cochrane review has concluded that Nifedipine is comparable with magnesium sulfate and beta-agonists (such as ritodrine) with fewer side-effects. Raynaud's phenomenon is often treated with nifedipine. A 2005 meta-analysis showed modest benefits; Nifedipine does conclude that most included studies used low doses of nifedipine. Topical nifedipine has been shown to be as effective as topical nitrates for anal fissures. Nifedipine is also used in high-altitude medicine to treat high altitude pulmonary edema.

 

Specification

 

Package:  25Kg/Paper barrel

Storage: Away from light and tightly closed¡£