Name:  Niclosamide

Synonyms:  Bayluscid; 2',5-Dichloro-4'-nitrosalicylanilide; 2-Hydroxy-5-chloro-N-(2-chloro-4-nitrophenyl)benzamide; 5-Chloro-2'-chloro-4'-nitrosalicylanilide; 5-Chloro-N-(2-chloro-4-nitrophenyl)salicylamide

Molecular Structure:  

Molecular Formula:  C₁₃H₈C_l2N₂O₄

Molecular Weight:  327.12

CAS Number:  50-65-7

EINECS:  200-056-8

 

Niclosamide (trade name Niclocide) is a teniacide ("tenia-" referring to tapeworm) in the anthelmintic family especially effective against cestodes that infect humans. Niclosamide is also used as a piscicide.It is stressed that while anthelmintics are a drug family used to treat worm infections, Niclosamide is used specifically to treat tapeworms and is not effective against worms such as pinworms or roundworms. Niclosamide is a chewable tablet taken orally, dosage depending on type of worm and patient's age and/or weight. Niclosamide molecules are lethal to tapeworms upon contact. Niclosamide is used to control of golden apple snail in rice; control of schistosomiasis and fascioliasis in man by killing fresh-water snails which act as intermediate hosts. Also Niclosamide is used for veterinary control of tapeworm infestations.

 

Specification