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Tilmicosin Phosphate

Name: Tilmicosin phosphate

Synonyms: 20-Deoxo-20-(3,5-dimethyl-1-piperidinyl)desmycosin phosphate

Molecular Structure:

Molecular Formula: C46H80N2O13.H3PO4

Molecular Weight: 967.14

CAS Number: 137330-13-3

 

Tilmicosin phosphate is a macrolide antibiotic synthesized from tylosin. Tilmicosin phosphate developed for veterinary use only, and has an antibacterial spectrum similar to tylosin with enhanced activity against Pasteurella haemolytica, P. multocida, Actinobacillus pleuropneumoniae, mycoplasma species and other microorganisms found sensitive to this compound. Tilmicosin phosphate is recommended for treatment and prevention of pneumonia in cattle, sheep, poultry and pigs. Not show resistance and cross-resistance with other antibiotic often used in clinic. Mainly used in the Pleuropneumonia and the infection caused by Pasteurellaceae , Pasteurella and mycoplasma.

 

Dosage: mix with feed, 400g/1000kg swine (active matter) for 15 days

 

Specification: According to USP30

Item

Specification

Characteristics

Almost white or yellowish powder

Identification

(1) The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.

(2) Complies with the Phosphate identification test

Related substances

Individual impurity: 3.0% Max.

Total impurities: 10.0% Max.

Water

5.0% Max.

pH

5.0 ~8.0

Appearance of solution

Clear, transparent and no visible evidence of contamination of foreign matter

Heavy metals

20ppm Max.

Tilmicosin Cis-isomers

82.0 ~ 88.0%

Tilmicosin Trans-isomers

12.0 ~ 18.0%

Assay of Tilmicosin

75.0% Min. (on dried basis)

 

Packing: 25kg/drum

View Veterinary Item.