Product Name:Avermectin B1a

Molecular Structure 

  

 

Molecular Formula :C₄₈H₇₂O₁₄

Molecular Weight:873.09

The avermectins are a series of macrocyclic lactone derivatives with potent anthelmintic properties. Other anthelmintics derived from the avermectins include ivermectin, selamectin, doramectin and abamectin.

A commonly used therapy in recent times has been based on oral or parenteral administration of avermectins, which are macrocyclic lactones produced by fermentation of various, carefully prepared laboratory broths using the soil micro-organism Streptomyces avermitilis. They show activity against a broad range of nematodes and arthropod parasites of domestic animals at dose rates of 300 microgram/kg or less. Unlike the macrolide or polyene antibiotics, they lack significant antibacterial or antifungal activity (Hotson, 1982).