Prodict Name:Amoxicillin

Synonyms :(2S,5R,6R)-6-(2-Amino-2-(4-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Molecular Structure

  

Molecular Formula¡±C₁₆H₁₉N₃O₅S

Molecular Weight¡±365.40

CAS Registry Number:26787-78-0

Amoxicillin (INN), formerly amoxycillin (BAN), is a moderate-spectrum, bacteriolytic, ¦Â-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms. It is usually the drug of choice within the class because it is better absorbed, following oral administration, than other ¦Â-lactam antibiotics.

Amoxicillin is susceptible to degradation by ¦Â-lactamase-producing bacteria, and so may be given with clavulanic acid to decrease its susceptibility.

Amoxicillin in trihydrate form is available as capsules, chewable and dispersable tablets plus syrup and pediatric suspension for oral use, and as the sodium salt for intravenous administration. It is one of the most common antibiotics prescribed for children, and the liquid forms are helpful where the patient might find it difficult to take tablets or capsules. It has three ionizable groups. A once daily dosing form (Moxatag) was approved by the American FDA in January 2008.