Name:  Acetylsalicylic acid

Synonyms:  2-Acetoxybenzoic acid; Aspirin

Molecular Structure:  

Molecular Formula:  C₉H₈O₄

Molecular Weight:  180.16

CAS Number:  50-78-2

EINECS:  200-064-1

 

Aspirin (USAN), also known as acetylsalicylic acid (ASA), is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication. Aspirin also has an antiplatelet effect by inhibiting thromboxane prostaglandins, which under normal circumstances bind platelet molecules together to repair damaged blood vessels. This is why aspirin is used in long-term, low doses to prevent heart attacks, strokes, and blood clot formation in people at high risk for developing blood clots. Aspirin has also been established that low doses of aspirin may be given immediately after a heart attack to reduce the risk of another heart attack or of the death of cardiac tissue

The main undesirable side effects of aspirin are gastrointestinal ulcers, stomach bleeding, and tinnitus, especially in higher doses. In children and adolescents, aspirin is no longer used to control flu-like symptoms or the symptoms of chickenpox or other viral illnesses, due to the risk of Reye's syndrome.

Aspirin was the first discovered member of the class of drugs known as non-steroidal anti-inflammatory drugs (NSAIDs), not all of which are salicylates, although they all have similar effects and most have inhibition of the enzyme cyclooxygenase as their mechanism of action. Today, aspirin is one of the most widely used medications in the world, with an estimated 40,000 metric tons of it being consumed each year. In countries where Aspirin is a registered trademark owned by Bayer, the generic term is acetylsalicylic acid (ASA).

Aspirin is an antipyretic ant rheumatic that is used to allay fever, headache, arthralgia, acticerheumatism, and rheumatoid arthritis. Toothache and dysmenorrhea and as raw material for making anti-carcinogen. 

 

Physical and Chemical Properties:

White crystal or crystalline powder, with acid taste and is stable in dry air, slowly hydrolyze into salicylic acid and acetic anhydride. Its solution shows and acid reaction. Sparingly soluble in alcohol, chloroform or ether, slightly soluble in water or absolute ether, it dissolves in alkali hydroxide or alkali carbonate solution and decomposes at the same time. 

Specification:

Assay: 99.50-101.0%

Clarity and color of solution: Clear and colorless

Heavy metals: ¡Ü20ppm 

Free salicylic acid: ¡Ü500ppm 

Sulfate: ¡Ü0.1%

Loss of drying: ¡Ü0.5% 

Addition Material: ¡Ü0.1% 

Appearance: white crystal or crystalline powder

 

Packing:  25kg in fiberboard-made pail attached with paper or polyethylene bag inside.

Storage: Seal up container in dry place.