Name:  Artemisinin

Synonyms:  (+)-Arteannuin; Qinghaosu; [3R-(3R,5aS,6S,8aS,9R,10R,12S,12aR**)]-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-one

Molecular Structure:  

Molecular Formula:  C₁₅H₂₂O₅

Molecular Weight:  282.33

CAS Number:  63968-64-9

 

Artemisinin is a kind of colorless needle-like crystal, bitter, easily soluble in acetone chloroform or benzene, soluble in methanol, ethanol etc. , almost insoluble in water, easily soluble in glacial acetic acid

Melting point:  150-153¡ãC.

Specific rotation:  +75¡ã to +78¡ã 

Drying loss:  No more than 0.5%.

Ignition residue:  No more than 0.1%.

Use:  Antimalarial

Packing:  25kg/drum

Storage:  Avoid light, sealed 

 

Artemisinin is a new-type antimalarial featuring low toxin, good effect and quick result. Artemisinin  is effective to both malignant malaria and tertian malaria.  Artemisinin  can be used for the first-aid for pernicious malaria and the treatment of chloroquine-resistance.

Artemisinin is a drug used to treat multi-drug resistant strains of falciparum malaria. The compound (a sesquiterpene lactone) is isolated from the plant Artemisia annua. Not all plants of this species contain artemisinin. Apparently it is only produced when the plant is subjected to certain conditions, most likely biotic or abiotic stress. Artemisinin can be synthesized from artemisinic acid. The drug is derived from a herb used in Chinese traditional medicine, though Artemisinin is usually chemically modified and combined with other medications.

Use of the drug by itself as a monotherapy is explicitly discouraged by the World Health Organization as there have been signs that malarial parasites are developing resistance to the drug. Combination therapies that include artemisinin are the preferred treatment for malaria and are both effective and well tolerated in patients. The drug is also being studied as a treatment for cancer.